Now it's freshman year of college for the winsome threesome, and the first semester is full of surprises. Bubbly Angela dives headfirst into sorority life, but faced with mean girls and hazing, she wonders whether she's a Greek girl after all. By choosing Santa Cruz, Maddie is finally surrounded by like-minded (i.e., not sorority-type) people, but feels lonelier than ever.

And Zoe is keeping up a long-distance relationship with Doug, her high school boyfriend. She thought they'd be together forever, but after a few awful visits not so much. In the face of all this change, what are the best friends to do? Make the most of every crazy moment, that's what. You only go to college once, after all.